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<groups>
<group>approved</group>
</groups>
<taxonomy>
<kingdom></kingdom>
<substructures/>
</taxonomy>
<synonyms/>
<salts>
<salt>Goserelin acetate</salt>
</salts>
<brands>
<brand>Zoladex</brand>
</brands>
<mixtures/>
<packagers>
<packager>
<name>AstraZeneca Inc.</name>
<url>http://www.astrazeneca.ca</url>
</packager>
</packagers>
<manufacturers>
<manufacturer generic="false">Astrazeneca uk ltd</manufacturer>
</manufacturers>
<prices>
<price>
<description>Zoladex 3.6 mg implant syringe</description>
<cost currency="USD">451.19</cost>
<unit>syringe</unit>
</price>
<price>
<description>Zoladex 10.8 mg implant syringe</description>
<cost currency="USD">1380.65</cost>
<unit>syringe</unit>
</price>
</prices>
<categories>
<category>Antineoplastic Agents</category>
<category>Antineoplastic Agents, Hormonal</category>
</categories>
<affected-organisms>
<affected-organism>Humans and other mammals</affected-organism>
</affected-organisms>
<dosages>
<dosage>
<form>Implant</form>
<route>Subcutaneous</route>
<strength></strength>
</dosage>
</dosages>
<atc-codes>
<atc-code>L02AE03</atc-code>
</atc-codes>
<ahfs-codes>
<ahfs-code>92:00.00</ahfs-code>
<ahfs-code>68:18.00</ahfs-code>
</ahfs-codes>
<patents>
<patent>
<number>7118552</number>
<country>United States</country>
<approved>2002-04-13</approved>
<expires>2022-04-13</expires>
</patent>
<patent>
<number>7500964</number>
<country>United States</country>
<approved>2001-02-26</approved>
<expires>2021-02-26</expires>
</patent>
</patents>
<food-interactions/>
<drug-interactions/>
<calculated-properties>
<property>
<kind>logP</kind>
<value>0.3</value>
<source>ALOGPS</source>
</property>
<property>
<kind>logS</kind>
<value>-4.7</value>
<source>ALOGPS</source>
</property>
<property>
<kind>Water Solubility</kind>
<value>2.83e-02 g/l</value>
<source>ALOGPS</source>
</property>
<property>
<kind>logP</kind>
<value>-5.2</value>
<source>ChemAxon</source>
</property>
<property>
<kind>IUPAC Name</kind>
<value>(2S)-1-[(2S)-2-[(2S)-2-[(2R)-3-(tert-butoxy)-2-[(2S)-2-[(2S)-3-hydroxy-2-[(2S)-2-[(2S)-3-(1H-imidazol-5-yl)-2-{[(2S)-5-oxopyrrolidin-2-yl]formamido}propanamido]-3-(1H-indol-3-yl)propanamido]propanamido]-3-(4-hydroxyphenyl)propanamido]propanamido]-4-methylpentanamido]-5-[(diaminomethylidene)amino]pentanoyl]-N-(carbamoylamino)pyrrolidine-2-carboxamide</value>
<source>ChemAxon</source>
</property>
<property>
<kind>Molecular Weight</kind>
<value>1269.4105</value>
<source>ChemAxon</source>
</property>
<property>
<kind>Monoisotopic Weight</kind>
<value>1268.641439486</value>
<source>ChemAxon</source>
</property>
<property>
<kind>SMILES</kind>
<value>CC(C)C[C@H](NC(=O)[C@@H](COC(C)(C)C)NC(=O)[C@H](CC1=CC=C(O)C=C1)NC(=O)[C@H](CO)NC(=O)[C@H](CC1=CNC2=CC=CC=C12)NC(=O)[C@H](CC1=CN=CN1)NC(=O)[C@@H]1CCC(=O)N1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N1CCC[C@H]1C(=O)NNC(N)=O</value> |
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